Maybe it is your first time to encounter this word. Do not worry. You are not alone. Millions of people do not know anything about Enobosarm. However, with the numerous potential positive effects of this newly introduced substance, it deserves to be known.
Here are some details about Enobosarm
1. It comes by the name Ostarine, too.
It is under the category of SARM or Selective Androgen Receptor Modulators. What is SARM? These are drugs that selectively target the tissues that need adrogenic effects. What are androgenic effects? Androgen is a male sex hormone such as testosterone. Its effects include the development of secondary sexual characteristics among males such as maturation of sex organs, deepening of voice, growth of facial, axillary and pubic hair. Also, this hormone is vital for increased muscle and bone mass.
2. Due to its ability to increase muscular mass and strength,
GTx, Inc originally developed this SARM medication for prevention and management of muscle wasting among non small cell lung cancer (NSCLC) patients. A study is conducted where a total of 325 patients with stage 3 or 4 NSCLC are either taking a daily dose of 3mg Ostarine or its placebo. The effects were being monitored by stages. The company’s hope was raised as the result of the three months experiment has demonstrated a significant effect statistically. Unfortunately, Enobosarm failed to achieve the agreed upon statistical significant difference required by Food and Drug Administration (FDA) for it to be filed as a new drug for treatment of muscle wasting for cancer patients. Still, the company believes that the data gathered during the clinical trial of the said drug may be enough to warrant the filing of MAA or marketing authorization application. Hence, the company is still evaluating the continuation of this research.
3. Why is it gaining popularity as SARM?
Prior to Enobosarm, the widely known and accepted SARM drug was anabolic steroids. However, there is a big gap between the two drugs in terms of the target of the drugs and its side effects. With anabolic steroids, tissues intended and not intended for the therapy were affected. For example, when the target tissue is just the skeletal system, even other tissues such as in testicles, prostate, hair, and the likes are also affected. So one could expect improvements on the skeletal system (such as increased bone density and mass) but will be dismayed with side effects like enlarged prostate or hair loss. With Enobosarm, the target of the drug is selective so the side effects are fewer. Meaning, if one intended it to increase physical performance or prevent muscle wasting, then that would be the focus of its actions. Other tissues would not be affected. Hence, you would not expect adrogenic responses such as shrinking testicles for males or deepening voice or enlarged clitoris for women, to name just a few possible side effects.
4. Aside from the original goal of preventing muscle wasting among cancer patients and those with skeletal and muscular disorders, the new drug is aiming to achieve the following in the future.
- Increase muscle strength, which could lead to better physical function both for the sick and the healthy individuals. Muscle wasting occurs because there is weakness of muscles and the individual therefore cannot use the muscles. The drug hopes to prevent this from happening by increasing muscle strength.
- Possibly decrease incidence of cases of Osteoporosis among the elderly females as bone density would increase with use of this drug.
- Hasten recovery of bone fractures or tendon injuries.
- Better alternative of athletes or sports enthusiasts for their bodybuilding programs.
Additional time and studies are required to determine the capabilities of this substance as a cure for muscle wasting. For now, researches are ongoing to make the conclusion credible and more substantial.Read more